Gastrointestinal cancers can be some of the most deadly types of tumors, but screening and treatments can make a difference.
Here's a rundown on the types of gastrointestinal cancers, along with their symptoms, treatments and tips for prevention.
Gastrointestinal (GI) cancer includes all cancers in your digestive tract organs. They are named in terms of the tissue where the disease started, not where it ended.
Ampullary cancer
Anal cancer
Bile duct cancer
Colon cancer
Esophageal cancer
Gallbladder cancer
Gastroesophageal cancer
Hepatocellular cancer
Pancreatic cancer
Rectal cancer
Small intestine cancer
Stomach cancer
The goal of screening tests is to detect cancers early in asymptomatic patients. Examples of screening tests are colonoscopy, endoscopy, endoscopic ultrasound and imaging. A primary care doctor often helps to determine which screening tests are indicated for which patients based upon a patient’s age, gender, medical history, family history, social history and genetics. For patients who present with symptoms, the first step is often seeking out a primary care physician who will order appropriate labs and tests to work up the symptoms. If a cancer is diagnosed, the primary care physician will then refer a patient to the appropriate specialist(s).
The treatment of cancer is a personalized decision determined by the patient and care team using evidence-based medicine and national/international guidelines. To determine the best treatment options, a multidisciplinary team made up of a medical oncologist, surgical oncologist, radiation oncologist, interventional radiologist, dietician, therapist, palliative care physician, and/or others may aid in the care of a patient with GI cancer.
The multidisciplinary team works early on to establish what kind of cancer a patient has, the stage of the cancer and where it has spread. Based upon this information, the team will determine if the goal of treatment is curative or palliative. While palliative care can be helpful no matter what the goal of treatment is to aid in symptom management, palliative treatment is an approach aimed at optimizing quality of life and relieving symptoms without a focus on the cause of the symptoms or its treatment. The multidisciplinary team will work together to come up with the best treatment plan for each patient using the following modalities of treatment:
Chemotherapy – Medicines that destroy cancer cells and stop their ability to grow
Targeted therapy – Drugs that are targeted at specific genetic pathway mutations that may be important for a given cancer’s growth and survival. This type of treatment blocks the growth and spread of cancer cells while limiting damage to healthy cells
Immunotherapy – Immunotherapy is a category of anti-cancer therapy that works by enlisting the body’s immune system to help detect and destroy cancer cells
Surgery – Surgery helps patients with localized cancers that have a chance to be cured by surgically removing the cancerous area(s)
Radiation therapy – Radiation therapy uses powerful beams of energy to destroy localized cancer cells and prevent them from growing. The beams can come from X-rays, protons or other sources
The best thing is to never get a gastrointestinal cancer at all. Here's what doctors, like those at Duke Cancer Center, suggest:
Stay active
See your primary care physician regularly, who will keep you up to date on recommended screenings
Maintain a healthy weight
Avoid smoking
Limit alcohol intake
Be aware of genetic risk factors and family history
Know the symptoms and see a doctor if you have concerns
Patients with GI cancer are encouraged to participate in clinical trials. This allows a patient access to novel treatments that they may not have otherwise been a candidate for and helps advance knowledge about how to treat GI cancers better.
For more information on the digestive system, check out these additional resources:
Stress and Stomach Pain: Diarrhea, Constipation, Ulcers & More
What's Causing Your Indigestion — And How to Treat It