What Is Chromium Picolinate? Do You Really Need It?

Chromium picolinate is a supplement that many folks take, as it's touted to unlock insulin, burn fat and build muscle.

But do you really need to add it to your diet when the mineral chromium is already present in many foods, albeit in tiny amounts?

"There is little evidence or support for chromium supplementation, though advertisements suggest it can enhance muscle mass and help with weight loss and insulin sensitivity," said Samantha Heller, a senior clinical nutritionist at NYU Langone Medical Center in New York City.

Low chromium levels can increase blood sugar, triglycerides and cholesterol levels, and increase the risk for diabetes and heart disease, according to Mount Sinai.

Chromium supplements have also been seen as helpful in reducing obesity, building muscle, lowering blood pressure and fighting depression. These uses, however, remain unproven.

Most people are getting a sufficient amount of chromium from their diet, according to study published in the Journal of Trace Elements in Medicine and Biology. So for most people, supplemental chromium is unnecessary.

The U.S. Food and Drug Administration allows only the following health claim for chromium picolinate dietary supplements:

"One small study suggests that chromium picolinate may reduce the risk of insulin resistance, and therefore possibly may reduce the risk of type 2 diabetes. FDA concludes, however, that the existence of such a relationship between chromium picolinate and either insulin resistance or type 2 diabetes is highly uncertain," the agency says.

Chromium from food is generally considered safe, but high-dose supplements can have consequences, according to Mount Sinai.

Side effects can include reducing the sugar-lowering effect of insulin, stomach irritation, itching and reddening of the skin. Fast or irregular heart rhythms, liver problems and kidney damage have also been reported.

People with liver or kidney problems, or those with anemia, should not use chromium without talking to their doctors.

Because of these potential side effects and interactions with medications, you should take supplements only under the supervision of a health care provider, Mount Sinai experts say.

Some of the drugs that chromium can interact with include antacids, like Tums, Mylanta, Nexium, Prevacid and Prilosec.

And if you already take diabetes medications, chromium might lower blood sugar levels to dangerous levels. These medications include insulin, metformin, Diabeta (glyburide), Glucotrol (glypizide) or Diabinese (chlorpropamide).

Also, nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, Advil, Motrin and Aleve can raise chromium levels in the body.

Meanwhile, steroids can lower chromium levels in the body. And if you take Synthroid (levothyroxine) to treat a hypoactive thyroid, chromium might lower the amount of the drug the body absorbs.

If you are taking any of these medications, you should speak with your doctor about the risk of taking chromium supplements.

"Chromium is present in many foods including fruits, vegetables, whole grains and poultry, so supplementation is generally unnecessary," Heller said, noting that chromium deficiency has not been reported in healthy populations and there are no definitive deficiency symptoms. Adequate intake for adult men is set at 35 mcg/day and for adult women, 25 mcg/day, she added.

Sources of chromium include:

• Whole grain breads and cereals

• Lean meats

• Cheeses

• Spices, such as black pepper and thyme

• Brewer's yeast

• Some bran cereals

• Pork kidneys and other organ meats

• Mushroom

• Oatmeal

• Prunes

• Nuts

• Asparagus

For more information on nutrition, check out these additional resources:

What Is the Mediterranean Diet, and How Can It Help You?

Plant-Based Diets: What Are They, and How Do You Start?

Do You Need an Insulin-Resistance Diet?

Do You Need to Take Supplements If You Eat a Healthy Diet?